New Preprint — AstraROLE + AstraSUIT for Full-Length Protein Annotation
Jul 3, 2025
Orbion’s latest twin models are now live on bioRxiv, collapsing an entire wet-lab triage workflow into a single forward pass:
10 labels in seconds. EC class, GO terms, pathways, cofactors, taxonomy, membrane type, TM count and localisation—all at once.
No motif left behind. Full-length ESM-2 embeddings plus physicochemical enrichments handle complete chains without windowing.
Top-tier accuracy. Macro-F1 up to 0.98 (membrane) and 0.97 (EC) on benchmark sets.
Why it matters: faster construct triage, fewer assay dead-ends, instant hypotheses even for de-novo or synthetic sequences.
📑 Read the preprint for the full recipe—including three case studies: https://www.biorxiv.org/content/10.1101/2025.06.21.660734v1
