Research Any Protein—Novel or Known—in Minutes
Orbion empowers you to upload any protein sequence—novel or known—and instantly predict structure, PTMs, ligands and binding sites, function and localization, stabilizing mutation, and experimental protocols. From orphan proteins to well-characterized targets, get deep insights and actionable protocols in minutes instead of weeks.
Current bioinformatics workflows are slow and disconnected.
Databases (UniProt, PDB) bioinformatics tools, and AI models fail for novel proteins. Manual integration across 10+ tools takes months of setup and weeks of analysis and data wrangling. You're piecing together incomplete and disconnected predictions, instead of getting comprehensive insights.
Databases Miss Novel Proteins
Databases only cover known proteins. Bioinformatics tools (BLAST, HHpred) fail without homologs. Novel or engineered proteins? You're starting from scratch with no annotations or protocols.
Juggling 10+ Tools
PTM prediction, binding sites, functional annotations, structure predictions. All require different disconnected tools. Each tool has different inputs and formats. You're manually stitching together disconnected predictions for hours.
Weeks of Analysis
AlphaFold takes hours. Models require manual formatting. Scans time out on large proteins. Combining 5-10 tools takes days of data wrangling. Each new protein restarts this painful process.
Introducing The Fastest Way to Explore Any Protein
Orbion replaces 10+ disconnected tools with one platform. Upload any protein and get structure, PTMs (39 types), binding sites (2M+ ligands), functional annotations, mutations, and protocols in under an hour. No manual integration. Just comprehensive insights, instantly.
Instant Blind Analysis
Upload any sequence and get structure, PTMs (39 types), binding sites (2M+ ligands), functional annotations, and expression compatibility—no homologs or experimental data required.
Residue-Level Insights
See which residues are modified, where ligands bind, which domains are conserved, and what's safe to mutate. Understand your protein before experiments.
Sequence to Experiments
Orbion delivers characterization and protocols in under an hour instead of 2-4 weeks. Iterate on designs, compare variants, and prioritize candidates before wet lab work. Compress months into days.
How Platform Works
Three simple steps replace hours of tool-hopping and manual integration. Get comprehensive insights in minutes.
Upload Your Protein
Paste your FASTA sequence, upload a file, or enter a UniProt ID. Works with any protein—novel or known, single chains or multi-chain complexes. No length limits up to 5120 residues per chain.
Comprehensive Analysis
Orbion's AI analyzes your protein using AlphaFold, AstraPTM2, AstraBIND, and AstraROLE2/SUIT2 models. In under an hour, review structure, PTMs, binding sites, functional domains, conservation, and functional annotations—all with confidence scores.
Guide Experiments
Use Bench to generate expression, purification, crystallization, and cryo-EM protocols. Use Stabilize to design stabilizing mutations, optimize constructs, and improve solubility. Export protocols and mutation designs for immediate use in the lab.
