The Platform

One Workspace, from Sequence to Bench-Ready

Four Engines, One Platform

Characterize a protein, rank stabilizing mutations, score and pick constructs, and generate the protocol — every angle in one tool, including the one a structure model skips: which construct actually expresses.

Rhodopsin
UniProt P08100 · PDB 1U19 · 348 aa
7 TM Helices
N-Glycosylation · N2 / N15Retinal · 11-cisPocket · E113 / K296Scored MutationsPalmitoylation · C322 / C323
Bound LigandBinding PocketPTM SitesScored Mutations
Illustrative Overlay · Every Read the Platform Makes, on One Structure

The Four Engines

Generate Options, Rank the Right Ones, Make Only the Winners

Each engine does one job well and hands off to the next — so a raw sequence becomes a short, ranked list of things actually worth putting on the bench.

Characterize

Read the Protein

Everything you can know about a protein from its sequence — structure and confidence, PTM sites, binding pockets, membrane topology, and disorder — before you order a single primer.

Structure & pLDDTPTM SitesBinding PocketsTopologyDisorder
Explore Characterize
EXTRACELLULARCYTOPLASMTM1TM2TM3TM4TM5TM6TM7ICL1ECL1ICL2ECL2ICL3ECL3GPPNCPTMBindingDisulfideTM helixpLDDT

Stabilize

Find the Mutations That Hold

Rank point mutations by predicted stability gain, so the stabilizing variants worth testing rise to the top instead of getting lost in a screen.

ΔTmΔΔGHotspot MapMutation Ranking
Explore Stabilize
VariantPredicted ΔTm
A112V / L156FPICK+4.6 °C
M74I+3.1 °C
T203S+2.4 °C
G88A+1.7 °C
K41R+0.9 °C
D57N−0.8 °C

Design

Score Constructs Before You Clone

Rank constructs by predicted expression yield — the strong signal — with an early developability read to flag the risky ones before you commit a plate.

Yield RankingSolubilityAggregationPTM LiabilitiesTag & Fusion
Explore Design
ConstructYieldDev
C-142PICK0.860.71
C-0610.810.77
C-2070.740.68
C-2330.690.64
C-0890.620.58

Bench

Turn Picks into a Protocol

Take the in-silico winners to a literature-grounded, step-by-step protocol — adapted to your target and your expression host.

Literature SearchAdaptive ProtocolsVector SelectionExpression Host
Explore Bench
Codon-OptimizeE. coli
Express + IMACNi-NTA
3SEC PolishSuperdex 200
4Thermal-Shift QCnanoDSF

How It Fits Together

Thousands Scored In Silico, a Handful Made

The point of the platform isn't to generate more candidates — it's to narrow them. Score everything computationally, and take only the top-ranked few to the lab.

From Thousands of Candidates to the Few Worth Making

Every construct and mutation, scored before a single one is built — so only the highest-ranked handful reaches the bench.

CandidatesOrbion scoringTo the bench

Proof on Your Targets

Numbers on Our Proteins Only Prove So Much

Every engagement starts with a prospective, blind benchmark on your own targets — so you see how the platform performs on the proteins you actually care about before you commit.

18,367
Proteins Benchmarked
78%
GPCR ΔTm Direction
Blind
On Your Targets

Security & Trust

Private. Secure. Yours.

Sequences are the most sensitive thing you own. They stay yours — never used to train models for anyone else, and never shared across customers.

Security & Trust

We Never Train on Your Data

Inference only — your sequences are processed, not learned from, and nothing crosses between customers.

Full IP Ownership

No royalties, no milestones, no hidden fees. Every prediction and result belongs to you.

EU-Hosted

Processed and stored in the EU under a DPA, and deleted whenever you ask.

ISO 27001 in Progress

Our ISMS is built to the standard, with certification underway. Policies available on request.

Bring Your Hardest Target

See how close the predictions land to your own lab data — on the proteins you actually care about, before you commit a single experiment.