The Platform

One Workspace, from Sequence to Bench-Ready

Four Engines, One Platform

Characterize a protein, rank stabilizing mutations, score and pick constructs, and generate the protocol — every angle in one tool, including the one a structure model skips: which construct actually expresses.

CharacterizeStabilizeDesignBench

The Four Engines

Generate Options, Rank the Right Ones, Make Only the Winners

Each engine does one job well and hands off to the next — so a raw sequence becomes a short, ranked list of things actually worth putting on the bench.

Characterize

Read the Protein

Everything you can know about a protein from its sequence — structure and confidence, PTM sites, binding pockets, membrane topology, and disorder — before you order a single primer.

Structure & pLDDTPTM SitesBinding PocketsTopologyDisorder
Explore Characterize
EXTRACELLULARCYTOPLASMTM1TM2TM3TM4TM5TM6TM7ICL1ECL1ICL2ECL2ICL3ECL3GPPNCPTMBindingDisulfideTM helixpLDDT

Stabilize

Find the Mutations That Hold

Rank point mutations by predicted stability gain, so the stabilizing variants worth testing rise to the top instead of getting lost in a screen.

ΔTmΔΔGHotspot MapMutation Ranking
Explore Stabilize
VariantPredicted ΔTm
A112V / L156FPICK+4.6 °C
M74I+3.1 °C
T203S+2.4 °C
G88A+1.7 °C
K41R+0.9 °C
D57N−0.8 °C

Design

Score Constructs Before You Clone

Rank constructs by predicted expression yield — the strong signal — with an early developability read to flag the risky ones before you commit a plate.

Yield RankingSolubilityAggregationPTM LiabilitiesTag & Fusion
Explore Design
ConstructYieldDev
C-142PICK0.860.71
C-0610.810.77
C-2070.740.68
C-2330.690.64
C-0890.620.58

Bench

Turn Picks into a Protocol

Take the in-silico winners to a literature-grounded, step-by-step protocol — adapted to your target and your expression host.

Literature SearchAdaptive ProtocolsVector SelectionExpression Host
Explore Bench
Codon-OptimizeE. coli
Express + IMACNi-NTA
3SEC PolishSuperdex 200
4Thermal-Shift QCnanoDSF

How It Fits Together

Thousands Scored In Silico, a Handful Made

The point of the platform isn't to generate more candidates — it's to narrow them. Score everything computationally, and take only the top-ranked few to the lab.

From Thousands of Candidates to the Few Worth Making

Every construct and mutation, scored before a single one is built — so only the highest-ranked handful reaches the bench.

CandidatesOrbion scoringTo the bench

Proof on Your Targets

Numbers on Our Proteins Only Prove So Much

Every engagement starts with a prospective, blind benchmark on your own targets — so you see how the platform performs on the proteins you actually care about before you commit.

18,367
Proteins Benchmarked
78%
GPCR ΔTm Direction
Blind
On Your Targets

Security & Trust

Private. Secure. Yours.

Sequences are the most sensitive thing you own. They stay yours — never used to train models for anyone else, and never shared across customers.

Security & Trust
  • ISO/IEC 27001:2022 CertifiedCertified by Tempo Audits Ltd
  • GDPR CompliantEU processing, DPA with SCCs

We Never Train on Your Data

Inference only — your sequences are processed, not learned from, and nothing crosses between customers.

Full IP Ownership

No royalties, no milestones, no hidden fees. Every prediction and result belongs to you.

EU-Hosted

Processed and stored in the EU under a DPA, and deleted whenever you ask.

ISO 27001 Certified

Our ISMS is certified to ISO/IEC 27001:2022 under UKAS accreditation. Certificate and Statement of Applicability on request.

Bring Your Hardest Target

See how close the predictions land to your own lab data — on the proteins you actually care about, before you commit a single experiment.