Characterize:

Protein Intelligence Engine

Characterize deciphers your protein’s function and context — from domains to PTMs and binding pockets — so you design smarter, faster experiments. Powered by Astra AI models, it integrates evolutionary signals and structural data to deliver residue-level, evidence-backed insights.

Protein function is scattered, noisy, and hard to trust.

Annotations are incomplete, evidence is hidden in papers, and context is missing — leaving teams to make critical design decisions half-blind.

Limited Scope

Sparse Annotations

Most proteins have partial or outdated functional data — key PTMs, binding pockets, or motifs go completely unreported.

Experimental Efforts

Scattered Evidence

Insights are buried across databases, papers, and lab notes, forcing researchers to reconcile conflicting data manually.

Missed Insights

Costly Missteps

Missing or misinterpreting a critical residue leads to failed experiments, wasted constructs, and misleading hypotheses downstream.

From Blind Spots to Complete Context with Characterize

Characterize turns your protein sequence into a full functional profile — domains, PTMs, pockets, and partners — so you see every residue in context and make better design calls before you touch the bench.

AI Predictions

Residue-Level Resolution

Characterize maps every residue’s potential role — from catalytic sites and motifs to PTMs and binding pockets — so you know what to preserve or probe.

Protein Understanding

Functional Context

See domain architecture, evolutionary conservation, subcellular localization, and interaction partners in one view, removing the guesswork from variant design.

Discovery

Evidence You Can Trust

Each prediction is shown with confidence scores and flags for uncertainty — helping you focus on what’s actionable, and what's exploratory.

FAQ

What is Orbion?

Orbion is an AI-driven platform that helps scientists stabilize, engineer, and purify proteins more efficiently. Orbion identifies the most promising ways to modify proteins (e.g., truncations, mutations) and pinpoints the optimal conditions for structure determination—whether by crystallography or cryo-EM.

How can I use Orbion?

You can upload your protein sequence and any available structural or functional information into the Orbion platform. Orbion will then analyze potential PTMs, functional sites, and instability hotspots, suggest stabilizing modifications, and recommend experimental conditions for purification and structure determination. Think of it as a virtual collaborator, offering insights to guide your lab experiments and streamline your R&D process.

Which proteins can Orbion work with?

Orbion is designed to handle a wide range of proteins, from small soluble enzymes to large multi-domain or membrane-bound complexes. Our models are especially effective for challenging or unstable proteins that are traditionally difficult to crystallize or resolve using cryo-EM.

How does Orbion provide predictions?

Orbion uses neural networks and other machine-learning approaches trained on extensive protein data. Orbion generates scientifically grounded predictions on where and how to modify a protein, as well as which conditions are most likely to yield high-quality structural data.

Is there a free option for academical or public research?

Yes! If you are a researcher in academia or a public institute, and want to use Orbion for your public research studies, you can access Orbion for free. Simply, sign up for our researcher program, and we'll provide you the access very soon.

FAQ

What is Orbion?

Orbion is an AI-driven platform that helps scientists stabilize, engineer, and purify proteins more efficiently. Orbion identifies the most promising ways to modify proteins (e.g., truncations, mutations) and pinpoints the optimal conditions for structure determination—whether by crystallography or cryo-EM.

How can I use Orbion?

You can upload your protein sequence and any available structural or functional information into the Orbion platform. Orbion will then analyze potential PTMs, functional sites, and instability hotspots, suggest stabilizing modifications, and recommend experimental conditions for purification and structure determination. Think of it as a virtual collaborator, offering insights to guide your lab experiments and streamline your R&D process.

Which proteins can Orbion work with?

Orbion is designed to handle a wide range of proteins, from small soluble enzymes to large multi-domain or membrane-bound complexes. Our models are especially effective for challenging or unstable proteins that are traditionally difficult to crystallize or resolve using cryo-EM.

How does Orbion provide predictions?

Orbion uses neural networks and other machine-learning approaches trained on extensive protein data. Orbion generates scientifically grounded predictions on where and how to modify a protein, as well as which conditions are most likely to yield high-quality structural data.

Is there a free option for academical or public research?

Yes! If you are a researcher in academia or a public institute, and want to use Orbion for your public research studies, you can access Orbion for free. Simply, sign up for our researcher program, and we'll provide you the access very soon.

FAQ

What is Orbion?

Orbion is an AI-driven platform that helps scientists stabilize, engineer, and purify proteins more efficiently. Orbion identifies the most promising ways to modify proteins (e.g., truncations, mutations) and pinpoints the optimal conditions for structure determination—whether by crystallography or cryo-EM.

How can I use Orbion?

You can upload your protein sequence and any available structural or functional information into the Orbion platform. Orbion will then analyze potential PTMs, functional sites, and instability hotspots, suggest stabilizing modifications, and recommend experimental conditions for purification and structure determination. Think of it as a virtual collaborator, offering insights to guide your lab experiments and streamline your R&D process.

Which proteins can Orbion work with?

Orbion is designed to handle a wide range of proteins, from small soluble enzymes to large multi-domain or membrane-bound complexes. Our models are especially effective for challenging or unstable proteins that are traditionally difficult to crystallize or resolve using cryo-EM.

How does Orbion provide predictions?

Orbion uses neural networks and other machine-learning approaches trained on extensive protein data. Orbion generates scientifically grounded predictions on where and how to modify a protein, as well as which conditions are most likely to yield high-quality structural data.

Is there a free option for academical or public research?

Yes! If you are a researcher in academia or a public institute, and want to use Orbion for your public research studies, you can access Orbion for free. Simply, sign up for our researcher program, and we'll provide you the access very soon.