AstraROLE2 & AstraSUIT2
Function and Experimental Suitability, from Sequence
Two companion models answer the first two questions about any protein. AstraROLE2 tells you what it does; AstraSUIT2 tells you how to work with it — so an unannotated sequence arrives already profiled for function and for the bench.
A Complete Protein Profile — From Sequence Alone
A ten-factor functional profile — function (EC, GO, pathways) and experimental suitability (cofactors, membrane type, topology) in one call, no MSA. It generalizes to low-homology, engineered, and de-novo proteins, where homology-based tools fall short.
Real Structure · Rhodopsin (PDB 1U19)
One Sequence, a Full Profile
Two Models, One Call
What It Does, and How to Work with It
Both read the same sequence and return a structured profile — no MSA hunt, no manual annotation.
AstraROLE2
What the Protein Does
- EC Number
- Enzyme Commission Classification
- GO Terms
- Molecular Function, Process, Component
- Categories
- Protein Type and Family
- Pathways
- Metabolic & Signalling Membership
AstraSUIT2
How to Work with It
- Cofactors
- Metals, Nucleotides, Prosthetic Groups
- Domains
- Fold Class and Domain Make-Up
- Host Lineage
- Eukaryota / Bacteria / Archaea / Virus
- Membrane Type
- Soluble, Integral, Peripheral, Anchored
- Localization
- Subcellular Compartment
- TM Helices
- Transmembrane Span Count
Example Read-Out
One Sequence, Fully Profiled
- Function
- G Protein-Coupled Photoreceptor
- GO
- Phototransduction · GPCR Signalling
- Category
- Class A (Rhodopsin-Like) GPCR
- Pathway
- Visual Phototransduction
- Cofactor
- Retinal (11-cis)
- Membrane
- Integral · Multi-Pass
- TM Helices
- 7
- Localization
- Photoreceptor Membrane
- Host Lineage
- Eukaryota
Illustrative Read-Out for a Well-Characterized Target.
Put Astra on Your Targets
Every Astra model runs inside the Orbion platform. Bring a sequence and get the full read-out — structure, function, modifications, binding, and stability.