AstraYIELD
Rank Constructs by Expression Yield
Most designed constructs never express well. AstraYIELD reads a construct sequence and predicts how much material it will produce — so you can rank a long panel of designs and take only the few most likely to work into the lab, instead of expressing them all.
Validated Before the Bench, Not After
On a blind, prospective panel — 24 constructs designed, scored, then measured at the bench without the results in hand — AstraYIELD's ranking tracked the measured yield. It called the low producers the shipped hand-tuned formula ranked at the top.
Prospective Validation
Ranked before the experiment, confirmed after
What It Does
A Shortlist, Not a Full Screen
Expression is the first place a design panel fails. AstraYIELD scores each construct so the bench time goes to the candidates most likely to produce material.
Rank a Panel
Every construct gets a yield score, so a long list of designs sorts down to the few worth expressing first.
Triage Before the Bench
Spend wet-lab effort on the constructs most likely to express, and skip the ones headed for the discard pile.
From Sequence Alone
No structure, no prior expression data — the score comes straight from the construct sequence.
Performance
Measured Against Real Expression
The headline number comes from a prospective, blind panel — constructs designed and scored, then expressed and measured at the bench, with the model's ranking checked against the outcome.
AstraYIELD is a ranking tool. It sorts a panel from most to least likely to express — strong enough to keep the failures off the bench — but it does not predict an absolute mg/mL for any single construct. Read it as expressibility triage across a set, not a yield forecast for one design in isolation.
In Context
Where It Runs
Put Astra on Your Targets
Every Astra model runs inside the Orbion platform. Bring a sequence and get the full read-out — structure, function, modifications, binding, and stability.